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Publications

Discover a comprehensive collection of Professor Veron Ramsuran’s groundbreaking publications in the fields of genomic medicine and infectious disease. Each publication is a step forward in advancing medical knowledge and improving health outcomes in Africa.

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Infectious Diseases

Maternal and Reproductive Health

Cancer and Precision Medicine

Genomics and Human Biology

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Assessment of the transcriptional and cellular effects of CRISPRa targeting Dopa decarboxylase and GTP cyclohydrolase 1 in HEK293 and SH-SY5Y cellular models of Parkinsonian neurotoxicity

Frontiers in Cellular Neuroscience

2026

Recent advances in the histopathology, molecular biology, and treatment of Kaposi sarcoma: a contemporary review

2025

A Review of Global Patterns in Gut Microbiota Composition, Health and Disease: Locating South Africa in the Conversation

2025

High resolution class I HLA-A, -B, and -C diversity in Eastern and Southern African populations

2025

Drug transporter mRNA expression and genital inflammation in South African women on oral pre-exposure prophylaxis (PrEP)

2025

Variation within the non-coding genome influences genetic and epigenetic regulation of the human leukocyte antigen genes

2024

Unique Gene Expression Profiles within South Africa Are Associated with Varied Chemotherapeutic Responses in Conventional Osteosarcoma

2024

HLA-B and C Expression Contributes to COVID-19 Disease Severity within a South African Cohort

2024

Narrative Review Explaining the Role of HLA-A, -B, and -C Molecules in COVID-19 Disease in and around Africa

2024

Host Genetic Impact on Infectious Diseases among Different Ethnic Groups

2023

Polymorphisms within the SARS-CoV-2 human receptor genes associate with variable disease outcomes across ethnicities

2023

Single-nucleotide polymorphisms in ABC drug transporters alter expression and circulating tenofovir in healthy South African women exposed to pre-exposure prophylaxis

2023

Genetic Variants within SARS-CoV-2 Human Receptor Genes May Contribute to Variable Disease Outcomes in Different Ethnicities

2023

A Systematic Review of the Heterogenous Gene Expression Patterns Associated with Multidrug Chemoresistance in Conventional Osteosarcoma

2023

Genetic ethnic differences in human 2′-5′-oligoadenylate synthetase and disease associations

2023

The association of polymorphisms and expression within TLR-4, -7 and ICAM-1 with specific prevalent sexually transmitted infections

2023

Early PD-1 expression on CD8+ T-cells and the development of a stem-like phenotype are associated with HIV slow-progression in children

2023

Comparison between qPCR and RNA-seq reveals challenges of quantifying HLA expression

2023

Editorial: Epigenetics of Infectious Diseases

2022

Evaluation of various alternative economical and high throughput SARS-CoV-2 testing methods within resource-limited settings

2022

Pharmacogenomics of drug transporters for antiretroviral long-acting pre-exposure prophylaxis for HIV

2022

Assessment of antibiotic resistance and efflux pump gene expression in Neisseria gonorrhoeae by quantitative real-time PCR and regression analysis

2022

The challenges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in low-middle income countries and possible cost-effective measures in resource-limited settings

2022

Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner

2022

The Effect of miRNA Gene Regulation on HIV Disease

2022

High-Resolution Melting Analysis to Detect Antimicrobial Resistance Determinants in South African Neisseria gonorrhoeae Clinical Isolates and Specimens

2022

Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection

2022

Tracking Antimicrobial Resistance in Neisseria gonorrhoeae from the Molecular Level Using Endocervical Swabs

2022

Deciphering DNA Methylation in HIV Infection

2021

An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults

2021

16S rRNA-based metagenomic profiling of microbes on contact surfaces within shared sanitation facilities

2021

Antimicrobial Resistance Mechanisms, Multilocus Sequence Typing, and NG-STAR Sequence Types of Diverse Neisseria gonorrhoeae Isolates in KwaZulu-Natal, South Africa

2021

Tracking Antimicrobial Resistance in Neisseria gonorrhoeae from the Molecular Level Using Endocervical Swabs

2021

Strong correlation between urine and vaginal swab samples for bacterial vaginosis

2021

SARS-CoV-2 and helminth co-infections, and environmental pollution exposure: An epidemiological and immunological perspective

2021

Transient association between semen exposure and biomarkers of genital inflammation in South African women at risk of HIV infection

2021

Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis

2021

Comparison of methods for the detection of Neisseria gonorrhoeae from South African women attending antenatal care

2021

Genome Sequences of Five Novel Neisseria gonorrhoeae Sequence Types Isolated in KwaZulu-Natal, South Africa

2021

Performance of TaqMan probes for the detection of sexually transmitted infections in South African women

2021

Quantitative detection of bacteria associated with BV in urine versus swab samples using droplet digital PCR

2020

Next generation sequencing and bioinformatics analysis of family genetic inheritance

2020

Assessing a diagnosis tool for bacterial vaginosis

2020

Prevalence of Genotypes and Subtypes of Gardnerella vaginalis in South African Pregnant Women

2020

Gene polymorphisms of uric acid are associated with pre-eclampsia in South Africans of African ancestry

2020

HLA-G Polymorphisms Associated with HIV Infection and Preeclampsia in South Africans of African Ancestry

2020

The Role of Highly Active Antiretroviral Therapy (HAART) on Interleukin 17A (IL-17A) in Normotensive and Preeclamptic Black South African Women

2020

Maternal variants within the apolipoprotein L1 gene are associated with preeclampsia in a South African cohort of African ancestry

2020

Genome-wide association study identifies HLA-DPB1 as a significant risk factor for severe aplastic anaemia

2020

Polymorphisms within vitamin D binding protein gene within a Preeclamptic South African population

2019

Effects of Genetic variability on Rifampicin and Isoniazid pharmacokinetics in South African patients with tuberculosis

2019

Pre-eclampsia: the role of highly active antiretroviral therapy and immune markers

2019

Variation in the untranslated genome and susceptibility to infections

2018

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

2018

Case report: mechanisms of HIV elite control in two African women

2018

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells

2018

P069UTR SNPS rs111686073 and rs73410010 independently modify expression of tapasin in blacks

2018

Effect of genetic variation in UGT1A and ABCB1 on moxifloxacin pharmacokinetics in South African patients with tuberculosis

2017

Hyperbilirubinemia in atazanavir-treated human immunodeficiency virus-infected patients: the impact of the UGT1A1*28 allele

2017

Sequence and Phylogenetic Analysis of the Untranslated Promoter Regions for HLA Class I Genes

2017

Posttranscriptional Regulation of HLA-A Protein Expression by Alternative Polyadenylation Signals Involving the RNABinding Protein Syncrip

2017

Follicular regulatory T cell dynamics in peripheral blood and lymphoid tissue during very early treatment initiation in HIV-1 clade C infection

2017

HLA-C expression level is regulated by a polymorphic Oct1 binding site in the HLA-C promoter region

2016

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor

2015

Epigenetic Regulation of Differential HLA-A Allelic Expression Levels

2015

Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract

2014

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease

2013

Duffy-Null-Associated Low Neutrophil Counts Influence HIV-1 Susceptibility in High-Risk South African Black Women

2011

Influence of Variations in CCL3L1 and CCR5 on Tuberculosis in a Northwestern Colombian population

2011